Michael J. Birrer

The paper uses single-cell RNA sequencing and flow cytometry to analyze myeloid cells in young and aged mouse ovaries, identifying aging-related changes in macrophage subsets and signaling pathways.

This study identifies germline genetic variants influencing somatic mutation patterns in 2,642 cancer genomes across 39 cancer types.

This paper shows that molecular subtypes and gene signatures in ovarian cancer are influenced by stromal cell content, suggesting that bulk tissue analysis may be unreliable without accounting for cell admixture.