Cell BiologybioRxivPreprint
Synergistic Role of Amino Acids in Enhancing mTOR Activation Through Lysosome Positioning
Oralia M. Kolaczkowski, Baley A. Goodson, Valeria F. Montenegro Vazquez…·Jing Pu
This study identifies amino acids that regulate lysosome positioning and shows that combining lysosome-dispersing amino acids with mTOR-activating ones synergistically enhances mTOR activation, particularly in cancer cells.