Author

Xuehua Xu

National Institutes of HealthORCID 0000-0002-3863-9593Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:Drosophila· 1 Assay:flow cytometry· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Tian JiniD· 3 shared Riley KIMiD· 2 shared Woo Sung KimiD· 2 shared arthur leeiD· 1 shared Arthur M. LeeiD· 1 shared Caleb ZhaoiD· 1 shared Haneul HyuniD· 1 shared Helen Su· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

Tian JinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Heterotrimeric G protein αi2 Sequesters RasGAP to Control Neutrophil Sensitivity and Chemotaxis

Xuehua Xu, Woo Sung Kim, arthur lee, Riley KIM, Caleb Zhao, Huie Jing, Helen Su, Tian Jin

The paper identifies CAPRI as a Gai2 effector that modulates Ras activity and neutrophil chemotaxis, revealing a concentration-dependent mechanism for chemotactic sensitivity.

bioRxiv · May 5, 2026 · PreprintImmunology

Heterotrimeric G Protein and RasGAP Coupling Drives Adaptation During Chemotaxis

Xuehua Xu, Riley KIM, Haneul Hyun, Ranti Dev Shukla, Tian Jin

This study identifies C2GAP1 as a RasGAP that couples with G2 to mediate adaptation during chemotaxis in Dictyostelium discoideum.

Cells · Apr 30, 2026Peer-reviewedCell Biology

PLCg2 Controls Neutrophil Sensitivity through Calcium Oscillation and Gates Chemoattractant Concentration Range for Chemotaxis

Xuehua Xu, Woo Sung Kim, Arthur M. Lee, Tian Jin

This study shows that PLCγ2 controls neutrophil sensitivity via calcium oscillations and regulates chemoattractant concentration range for chemotaxis.

bioRxiv · Apr 7, 2025 · PreprintCell Biology