Tian Jin

The paper identifies CAPRI as a Gai2 effector that modulates Ras activity and neutrophil chemotaxis, revealing a concentration-dependent mechanism for chemotactic sensitivity.

This study identifies C2GAP1 as a RasGAP that couples with G2 to mediate adaptation during chemotaxis in Dictyostelium discoideum.

This study shows that PLCγ2 controls neutrophil sensitivity via calcium oscillations and regulates chemoattractant concentration range for chemotaxis.

The paper generates a high-confidence mitochondrial protein compendium in Dictyostelium discoideum using proteomic and computational methods, identifying 1082 proteins and highlighting unique features compared to other organisms.

CRISPR-E measures gene essentiality by analyzing mutation patterns in surviving cells after CRISPR/Cas9 targeting.