Woo Sung Kim

This study shows that folic acid polyglutamylation activates MAP2K5 signaling to promote adipocyte lipid breakdown, revealing a novel role for folate in lipid homeostasis.

This study shows that liver-specific SCD1 deficiency reduces hyperglycemia and hepatic steatosis in T1D through bile acid-FXR-Glut1 signaling, independent of insulin.

The paper identifies CAPRI as a Gai2 effector that modulates Ras activity and neutrophil chemotaxis, revealing a concentration-dependent mechanism for chemotactic sensitivity.

The paper identifies a gut microbial metabolite of methotrexate that alleviates gut inflammation by promoting mitochondrial STAT3 signaling.

This study shows that PLCγ2 controls neutrophil sensitivity via calcium oscillations and regulates chemoattractant concentration range for chemotaxis.