Wei Liu

The paper shows that reduced brain growth in ciliary transition zone mutants causes premature facial fusion by mechanically forcing facial prominences into convergence.

The paper analyzes 3D micro-CT images of chicken embryos to show that primary palatal fusion creates a structurally constrained shape window during craniofacial development.

This paper introduces tFold-Ab and tFold-Ag for fast and accurate prediction of antibody and antibody-antigen complex structures, showing improved speed and performance over AlphaFold-Multimer.

tFold-Ab predicts antibody structures end-to-end without sequence homologs, achieving accuracy for both backbone and side-chain conformations.

MusMorph provides standardized mouse morphology data for meta-analyses, including craniofacial and brain structures across developmental stages and genotypes.

The paper develops a process-centered multivariate genotype-phenotype approach to analyze craniofacial shape variation in mice, linking gene sets to shape axes and predicting phenotypic effects beyond shape.

This paper applies a landmark-free morphometric method to a mouse model of Down syndrome, revealing localized cranial phenotypes not detectable with traditional landmark-based approaches.

This study identifies 37 QTL for facial shape in DO mice, finding enrichment for genes involved in skeletal and facial development, despite small individual effects.