ImmunologyJCI InsightPeer-reviewed
Polyfunctional IL-21+ IFNg+ T follicular helper cells contribute to checkpoint inhibitor diabetes mellitus and can be targeted by JAK inhibitor therapy
Nicole Huang, Jessica Ortega, Kyleigh Kimbrell…·Melissa G. Lechner
This paper identifies polyfunctional IL-21+ IFNγ+ T follicular helper cells as drivers of ICI-induced diabetes and shows JAK inhibitors can prevent this autoimmune condition.
4 citations