Alex Clop

This study constructs a multi-tissue cell atlas of pigs, identifies cell-type-specific gene regulation, and links these to complex traits and human phenotypes.

The paper performs a multi-breed meta-GWAS in pigs to identify genomic regions associated with complex traits and integrates with PigGTEx to prioritize variant-gene-tissue-trait circuits.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

The paper uses micrococcal nuclease sequencing on porcine sperm to identify nucleosomal fractions and links them to semen quality and early embryo development.

The paper identifies piRNAs in porcine sperm and finds correlations between their abundances and semen quality traits, with many located near transposable elements and fertility-related genes.

The paper characterizes the porcine sperm microbiome using RNA-seq, identifying bacterial phyla, potential pathogens, and antibiotic resistance genes associated with semen quality traits.

This study identifies circRNAs in porcine sperm and links some to sperm motility, suggesting potential as biomarkers for male fertility.

This study characterizes the porcine sperm transcriptome through RNA-seq, identifying seasonal changes in gene and microRNA expression related to oxidative stress and DNA damage.

The paper analyzes mitochondrial diversity in Italian pig breeds and wild boars, finding low diversity in pigs consistent with population bottlenecks and suggesting the E2 haplogroup was rare during domestication.