Bingjie Li

Genomic signatures of long-term selection in the Langhill dairy herd: the power of a five-decade experiment for sustainable dairy cattle breeding

This study analyzes genomic changes in a 50-year dairy cattle selection experiment, finding increased inbreeding and localized genetic differentiation in the selected line.

The enhanced multi-tissue atlas of regulatory effects in cattle

The paper presents CattleGTEx, a resource characterizing regulatory effects in cattle, resolving GWAS signals and providing insights into adaptive evolution and selection.

Integrating temporal genomic and transcriptomic analyses to decipher genetic basis of feed intake in dairy cattle

This study integrates genomic and transcriptomic analyses across lactation stages in dairy cattle to identify temporal genetic variants and molecular mechanisms associated with feed intake.

Metabolite profiles distinguish exposure to Dengue and Zika flaviviruses in human induced pluripotent stem cells (hiPSCs)

This study uses metabolomics to distinguish Dengue and Zika virus infections in hiPSCs, identifying virus-specific metabolic signatures and pathways that regulate viral replication.

A multi-tissue atlas of genetic regulatory effects in sheep

The paper presents a multi-tissue sheep atlas identifying regulatory variants and their effects on molecular phenotypes, revealing allelic heterogeneity and evolutionary patterns.

Genetic score omics regression and multi-trait meta-analysis detect widespread cis-regulatory effects shaping bovine complex traits

GSOR and MTAO detect widespread cis-regulatory effects on bovine complex traits by linking gene expression with genetic scores and multi-trait associations.

An atlas of cell type specific regulatory effects in cattle

The paper constructs a cattle cell-type-specific regulatory variant atlas by integrating bulk and single-cell RNA-seq data, identifying eQTL and linking them to GWAS loci for breeding insights.

The ChickenGTEx pilot analysis: a reference of regulatory variants across 28 chicken tissues

The ChickenGTEx project provides a multi-tissue reference of regulatory variants in chicken, analyzing their functional impacts and utility in genetics, genomics, and evolutionary studies.

Integrating large-scale meta-GWAS and PigGTEx resources to decipher the genetic basis of complex traits in pig.

The paper performs a multi-breed meta-GWAS in pigs to identify genomic regions associated with complex traits and integrates with PigGTEx to prioritize variant-gene-tissue-trait circuits.

A compendium of genetic regulatory effects across pig tissues

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

FarmGTEx TWAS-server: an interactive web server for customized TWAS analysis in both human and farm animals

The paper introduces a web server for multi-species transcriptome-wide association study (TWAS) analysis, enabling gene expression prediction and trait association in humans and farm animals.

A comprehensive catalogue of regulatory variants in the cattle transcriptome

The paper constructs a cattle Genotype-Tissue Expression atlas and identifies genetic regulatory variants linked to gene expression and traits in cattle.