Jordi Llorens

This study shows that ototoxicity in rats causes loss of vestibular type I hair cells, which correlates with deficits in tail-lift and air-righting reflexes, with different dependencies on specific regions.

This study links vestibular function loss in vestibular schwannoma patients to sensory epithelium pathology, including reduced hair cell counts and calyx damage.

The paper investigates the relationship between hair cell integrity and vestibular function, finding that 50% of hair cells are needed for minimal function and 80% for normal function.

The paper identifies gene expression changes in the vestibular sensory epithelium during chronic ototoxicity, finding early downregulation of HC-specific genes and upregulation of stress mediators across species and compounds.

The paper shows that vestibular calyceal junction dismantlement occurs in rats with streptomycin-induced ototoxicity and in human sensory epithelia under stress, preceding hair cell loss.

This study investigates subchronic vestibular hair cell damage in mice, showing partial loss affects VOR and OKR, with reduced visuo-vestibular integration despite VOR recovery.

This study examines how loss of vestibular hair cells in rats correlates with deficits in two anti-gravity reflexes, finding that type I hair cells are more sensitive to ototoxic damage than type II cells.

This study quantifies anti-gravity reflexes in rats to assess vestibular dysfunction using acute and sub-chronic IDPN exposure, showing dose- and time-dependent impairments.