Alejandro Barrallo‐Gimeno

The paper identifies gene expression changes in the vestibular sensory epithelium during chronic ototoxicity, finding early downregulation of HC-specific genes and upregulation of stress mediators across species and compounds.

The paper shows that vestibular calyceal junction dismantlement occurs in rats with streptomycin-induced ototoxicity and in human sensory epithelia under stress, preceding hair cell loss.

This study examines how loss of vestibular hair cells in rats correlates with deficits in two anti-gravity reflexes, finding that type I hair cells are more sensitive to ototoxic damage than type II cells.