Mireia Borrajo

This study links vestibular function loss in vestibular schwannoma patients to sensory epithelium pathology, including reduced hair cell counts and calyx damage.

The paper identifies gene expression changes in the vestibular sensory epithelium during chronic ototoxicity, finding early downregulation of HC-specific genes and upregulation of stress mediators across species and compounds.

The paper shows that vestibular calyceal junction dismantlement occurs in rats with streptomycin-induced ototoxicity and in human sensory epithelia under stress, preceding hair cell loss.