Aïda Palou

This study shows that ototoxicity in rats causes loss of vestibular type I hair cells, which correlates with deficits in tail-lift and air-righting reflexes, with different dependencies on specific regions.

The paper investigates the relationship between hair cell integrity and vestibular function, finding that 50% of hair cells are needed for minimal function and 80% for normal function.

The paper identifies gene expression changes in the vestibular sensory epithelium during chronic ototoxicity, finding early downregulation of HC-specific genes and upregulation of stress mediators across species and compounds.

This study investigates subchronic vestibular hair cell damage in mice, showing partial loss affects VOR and OKR, with reduced visuo-vestibular integration despite VOR recovery.