A novel AAA+ ATPase required for sporulation and stress response in Bacillus anthracis
Nitika Sangwan, Ankur Bothra, Andrei P. Pomerantsev, Aakriti Gangwal, Rasem J. Fattah, Mahtab Moayeri, Qian Ma, Sundar Ganesan, Chetkar Chandra Keshavam, Renu Baweja, Uma Dhawan, Stephen Howard Leppla, Yogendra Prakash Singh
This study identifies BAS PrkA, a novel AAA+ ATPase in B. anthracis, which is essential for sporulation and osmotic stress response, despite lacking detectable enzymatic activity.
Journal of Bacteriology · Feb 19, 2026Peer-reviewedMicrobiology