Author

Andrew P. Thompson

The University of MelbourneORCID 0000-0002-3910-2317Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Amelia Henley· 1 shared Annette von DelftiD· 1 shared Anthony T. PapenfussiD· 1 shared Anya Robinson· 1 shared Carmen Jimenez Antunez· 1 shared Daniel ZaidmaniD· 1 shared Dylan SilkeiD· 1 shared Eleanor P. Williams· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Amelia Henley

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 11, 2026

Discovery of a molecular glue inhibitor that stabilises a non-productive Kalirin-Rac1 complex

Janine L. Gray, Mia C. Callens, Amelia Henley…·Paul E. Brennan

The paper identifies covalent molecular glue inhibitors that stabilize a non-productive Kalirin-Rac1 complex, inhibiting nucleotide exchange and reducing GEF turnover.

DOI 10.64898/2026.09.08.749156

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioinformaticsProtein SciencePeer-reviewedJan 21, 2026

ProteinDJ: a high-performance and modular protein design pipeline

Dylan Silke, Julie Iskander, Junqi Pan…·Joshua M. Hardy

ProteinDJ is a high-performance protein design pipeline that enables efficient generation and testing of synthetic protein binders using HPC systems.

6 citationstop 1%

protein sequencedeep learning

𝕏 PostBluesky