Author

Paul S. Miclea

Charles UniversityORCID 0000-0002-3910-4574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Josef LazariD· 2 shared Alexey BondariD· 1 shared Alina SakhiiD· 1 shared Annu Dalal· 1 shared Arun K. ShuklaiD· 1 shared Divyanshu Tiwari· 1 shared Gargi MahajaniD· 1 shared Jitka MyškováiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

Josef LazarORCID

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2 papers

Recent·Most cited

PhysiologyScience AdvancesPeer-reviewedJan 16, 2026

Novel Genetically Encoded Probes for Functional Imaging of Cell Signaling by Polarization Microscopy

Paul S. Miclea, Vendula Nagy-Marková, Robin Van den Eynde…·Josef Lazar

This paper introduces FLIPs, a new class of genetically encoded biosensors that enable real-time single-cell imaging of cell signaling without modifying target proteins.

3 citations

fluorescence / live-cell microscopyexperimental assay

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BiochemistryProceedings of the National Academy of SciencesPeer-reviewedSep 9, 2025

A genetically-encoded nanobody sensor reveals conformational diversity in beta-arrestins orchestrated by distinct seven transmembrane receptors

Parishmita Sarma, Vendula Marková, Annu Dalal…·Arun K. Shukla

This study introduces a nanobody sensor to detect conformational changes in beta-arrestins upon GPCR activation, revealing receptor-specific conformational diversity.

4 citations

humanimaging

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