Josef Lazar

This paper introduces FLIPs, a new class of genetically encoded biosensors that enable real-time single-cell imaging of cell signaling without modifying target proteins.

This study introduces a nanobody sensor to detect conformational changes in beta-arrestins upon GPCR activation, revealing receptor-specific conformational diversity.

The paper measures two-photon absorptivity tensors of fluorescent proteins to understand their directionality and provides insights for biosensor development.