Author

Divyanshu Tiwari

Indian Institute of Technology Kanpur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:structural biology· 4 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Annu Dalal· 4 shared Arun K. ShuklaiD· 4 shared Manisankar Ganguly· 4 shared Manish Kumar YadaviD· 4 shared Nabarun RoyiD· 4 shared Nilanjana BanerjeeiD· 4 shared Ramanuj BanerjeeiD· 4 shared Sudha MishraiD· 4 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBiochemistry

Annu Dalal

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4 papers

Recent·Most cited

Molecular mechanism of naturally-encoded signaling-bias at the complement anaphylatoxin receptors

Divyanshu Tiwari, Kazuhiro Sawada, Annu Dalal, Sudha Mishra, Xaria X. Li, Joshua C Dent, Kiae Kim, Manish Kumar Yadav, Nabarun Roy, Manisankar Ganguly, Nilanjana Banerjee, Tomasz Maciej Stępniewski, Donghoon Ahn, Kohei Yamaguchi, Hidetaka S. Oshima, , Arun K. Shukla

This paper identifies naturally-encoded signaling bias at C5aR1 and C5aR2 receptors through structural and functional analyses, revealing molecular mechanisms underlying biased signaling in GPCRs.

Molecular Cell · Jun 22, 2026Peer-reviewedBiochemistry

Molecular basis of promiscuous chemokine-engagement by the Duffy antigen receptor

Manisankar Ganguly, Yuma Matsuzaki, Nabarun Roy, Divyanshu Tiwari, Sameer S. Kulkarni, Annu Dalal, Manish Kumar Yadav, Nilanjana Banerjee, Sudha Mishra, Kazuhiro Sawada, Kana M. Hashimoto, Kohei Yamaguchi, Martin J. Stone, Richard J. Payne, Andy Chevigné, , Arun K. Shukla

This study determines the cryo-EM structures of DARC bound to chemokines CCL7 and CXCL8, revealing unique binding mechanisms and the role of tyrosine sulfation and allelic variation in chemokine engagement.

bioRxiv · Mar 10, 2026 · PreprintBiochemistry

Atypical activation and molecular glue-like dimerization mechanism of an intrinsically-biased chemokine receptor

Nilanjana Banerjee, Manisankar Ganguly, Ashna Reyaz, Sudha Mishra, Annu Dalal, Xue Guo, Xingyu Qiu, Max Meyrath, Christie B. Palmer, Hongchen Guo, Siyuan Song, Shachie Sinha, Nabarun Roy, Debdatta Mukherjee, Divyanshu Tiwari, , Arun K. Shukla

This study reveals an atypical activation mechanism of CXCR7, identifies its role as an opioid receptor, and highlights potential for novel pain therapeutics.

bioRxiv · Oct 30, 2025 · PreprintBiochemistry

Molecular fingerprints of a convergent mechanism orchestrating diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptors

Sudha Mishra, Manish Kumar Yadav, Annu Dalal, Manisankar Ganguly, Ravi Yadav, Kazuhiro Sawada, Divyanshu Tiwari, Nabarun Roy, Nilanjana Banerjee, Jenny N. Fung, Jianina Marallag, Cedric S. Cui, Xaria X. Li, John D. Lee, Calvin Aaron Dsouza, , Arun K. Shukla

This study identifies a convergent molecular mechanism and species-specific pharmacology in complement anaphylatoxin receptors through structural and functional analyses of ligand-receptor interactions.

bioRxiv · May 26, 2025 · PreprintBiochemistry