Amato J. Giaccia

This study shows that low-dose radiopharmaceutical therapy enhances the effectiveness of B7-H3 CAR T cells in treating metastatic neuroblastoma in mice.

This study shows targeting C5aR1 reduces radiation-induced intestinal injury by promoting macrophage phenotypes that decrease stem cell apoptosis and improve tumor response.

This study shows FLASH RT increases lipid peroxidation and ferroptosis in tumors but not normal tissues, and high-iron diets negate FLASH's protective effect in normal tissues.

This paper shows that low-dose radiopharmaceutical therapy enhances GD2 TRAC-CAR T cell efficacy in neuroblastoma by improving tumor regression and immune response.

The paper introduces Pi-ATAC, a method combining single-cell chromatin and proteomic profiling, revealing hypoxia's role in shaping the regulome in tumor cells.