Yawei Wu

The paper introduces a long-range MPRA assay to measure enhancer-promoter interactions and finds that enhancer strength and transcription factor binding influence long-range activity.

The paper uses active learning to improve models of enhancer and silencer activities in mouse retina, achieving better discrimination between functionally distinct TF binding sites.

The paper develops MPIRE to assess insulator activity across the genome, finding that insulators function in specific genomic contexts and depend on transcription factor binding.