Organ-specific rewiring of mitochondrial integrity through COX7A dictates cellular ploidy control
Archan Chakraborty, Sophia DeLuca, Meera Gangasani, Stephen L. Rogers, Nenad Bursac, Donald T. Fox
The paper identifies COX7A as a regulator of cardiac polyploidy by modulating mitochondrial integrity, showing opposing roles in heart and salivary gland tissues.
bioRxiv · Sep 29, 2025 · PreprintDevelopmental Biology