Donald T. Fox

The paper introduces iSPy, an unsupervised learning pipeline for spatial ploidy inference from intact tissue images, demonstrating its use in Arabidopsis, Drosophila, and human tissues.

The paper identifies COX7A as a regulator of cardiac polyploidy by modulating mitochondrial integrity, showing opposing roles in heart and salivary gland tissues.

The paper identifies a gene that promotes viability in cells with centrosome amplification and multipolar division by positioning centrosomes at the plasma membrane.

The paper identifies Loofah, an adhesion protein, as a suppressor of cell death in long-lived Drosophila hindgut enterocytes by maintaining FasIII membrane localization.

This paper introduces ReFLeCT, a high-speed volumetric fluorescence imaging technique that captures 4D videos of freely moving zebrafish and Drosophila larvae with high-resolution 3D reconstruction.

This study identifies conserved polyploidy asymmetry between cardiac chambers in Drosophila and humans, showing its role in maintaining heart function and its implications for heart failure.

The paper shows that Orb2 regulates rare-codon-enriched mRNA expression in Drosophila neurons, impacting mGluR function and social behavior.

The paper identifies tissue-specific responses to rare codons in Drosophila, showing unique expression capabilities in testis and brain and a role for rare codons in restricting protein expression in the testis.

The paper shows that the Drosophila hindgut regenerates by accelerating the mitotic cell cycle during development, requiring JAK/STAT signaling and regulated by ecdysone receptor and Dichaete.

The paper identifies RpS21 as a signal strength-dependent regulator of the Ras/MAPK pathway using codon usage manipulation in Drosophila.

The paper shows that Drosophila intestinal stem cells at the midgut-hindgut boundary are regulated by inter-organ JAK-STAT signaling, with injury activating stem cell division.