Author

Marissa K. Oram

Boston UniversityORCID 0000-0002-3946-0296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:rat· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam J. Harvey· 1 shared Alistair T. PagnamentaiD· 1 shared Anja‐Katrin BielinskyiD· 1 shared Bérénice ChavaneliD· 1 shared Cécilia Sirand· 1 shared Claire RenardiD· 1 shared Colette B. RogersiD· 1 shared Debashree BasuiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Adam J. Harvey

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Human cancer genomes harbor the mutational signature of tobacco-specific nitrosamines NNN and NNK

Michael Korenjak, Nuri A. Temiz, Stéphane Keïta, Bérénice Chavanel, Claire Renard, Cécilia Sirand, Vincent Cahais, Tanguy Mayel, Karin R. Vevang, Foster C. Jacobs, Jiehong Guo, William E. Smith, Marissa K. Oram, Flaviu Tăbăran, Ozan Ahlat, , Jiří Zavadil

The paper identifies mutational signatures in cancer genomes caused by tobacco-specific nitrosamines NNN and NNK, showing their unique contribution to specific cancer types.

Genome Medicine · Jul 2, 2026Peer-reviewedGenomics

Bi-allelic MCM10 mutations cause telomere shortening with immune dysfunction and cardiomyopathy

Ryan M. Baxley, Wendy Leung, Megan Schmit, Jacob P. Matson, Lulu Yin, Marissa K. Oram, Liangjun Wang, John Taylor, Jack Hedberg, Colette B. Rogers, Adam J. Harvey, Debashree Basu, Jenny C. Taylor, Alistair T. Pagnamenta, Helene Marie-Pierre Dreau, , Anja‐Katrin Bielinsky

This study identifies bi-allelic MCM10 mutations causing telomere shortening, immune dysfunction, and cardiomyopathy by impairing DNA replication and telomerase activity.

Nature Communications · Mar 12, 2021Peer-reviewedMolecular Biology