Author

Changyu Sun

Johns Hopkins UniversityORCID 0000-0002-3964-1783Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Research Focus:clustering· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Dong Won KimiD· 4 shared Seth BlackshawiD· 4 shared Elizabeth ManningiD· 2 shared Elsie PlaceiD· 2 shared Ian GrovesiD· 2 shared Marysia PlaczekiD· 2 shared Parris Whitney Washington· 2 shared Sarah Burbridge· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersDevelopmental Biology

Dong Won KimORCID

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4 papers

Recent·Most cited

Developmental BiologyeLifePeer-reviewedJan 31, 2023

A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus

Kavitha Chinnaiya, Sarah Burbridge, Aragorn Jones…·Marysia Placzek

This study identifies a BMP signaling wave that drives anteroposterior specification of the tuberal hypothalamus in chicken embryos.

21 citations

scRNA-seqstatistical model

𝕏 PostBluesky

Developmental BiologyCell ReportsPeer-reviewedJan 1, 2022

Single-cell analysis of early chick hypothalamic development reveals that hypothalamic cells are induced from prethalamic-like progenitors.

Dong Won Kim, Elsie Place, Kavitha Chinnaiya…·Seth Blackshaw

This study uses single-cell RNA-Seq to analyze early chick hypothalamic development, revealing that hypothalamic cells originate from prethalamic-like progenitors and identifying novel molecular regulators.

37 citations

scRNA-seqstatistical model

𝕏 PostBluesky

NeuroscienceCommunications BiologyPeer-reviewedJan 21, 2021

Gene regulatory networks controlling differentiation, survival, and diversification of hypothalamic Lhx6-expressing GABAergic neurons.

Dong Won Kim, Kai Liu, Zoe Qianyi Wang…·Seth Blackshaw

This study identifies molecular mechanisms controlling the development of hypothalamic GABAergic neurons expressing Lhx6, showing their distinct regulatory networks compared to cortical interneurons.

60 citationstop 3%

mousestatistical model

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NeurosciencebioRxivPreprintApr 4, 2020

Single cell RNA-Seq analysis identifies molecular mechanisms controlling hypothalamic patterning and differentiation.

Dong Won Kim, Parris Whitney Washington, Zoe Qianyi Wang…·Seth Blackshaw

The paper uses scRNA-Seq to analyze mouse hypothalamic development, identifying gene expression trajectories and regional subdivisions, and reveals Nkx2.1 as a negative regulator of prethalamic identity.

10 citations

𝕏 PostBluesky