Author

Elizabeth Manning

University of SheffieldORCID 0000-0002-1372-381XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Organism:mouse· 1

Frequent Co-Authors

Marysia PlaczekiD· 4 shared Elsie PlaceiD· 3 shared Kavitha ChinnaiyaiD· 3 shared Seth BlackshawiD· 3 shared Changyu SuniD· 2 shared Dong Won KimiD· 2 shared Ian GrovesiD· 2 shared Sarah Burbridge· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersDevelopmental Biology

Marysia PlaczekORCID

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4 papers

Recent·Most cited

Resolving forebrain developmental organisation by analysis of differential growth patterns

Elizabeth Manning, Kavitha Chinnaiya, Caitlyn Furley, Dong Won Kim, Seth Blackshaw, Marysia Placzek, Elsie Place

The paper uses fate mapping and 4D modeling to reveal modular growth patterns in the chick forebrain, challenging the prosomere model and proposing a tripartite hypothalamus model.

Nature Communications · Dec 21, 2025Peer-reviewedDevelopmental Biology

A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus

Kavitha Chinnaiya, Sarah Burbridge, Aragorn Jones, Dong Won Kim, Elsie Place, Elizabeth Manning, Ian Groves, Changyu Sun, Matthew Towers, Seth Blackshaw, Marysia Placzek

This study identifies a BMP signaling wave that drives anteroposterior specification of the tuberal hypothalamus in chicken embryos.

eLife · Jan 31, 2023Peer-reviewedDevelopmental Biology

Single-cell analysis of early chick hypothalamic development reveals that hypothalamic cells are induced from prethalamic-like progenitors.

Dong Won Kim, Elsie Place, Kavitha Chinnaiya, Elizabeth Manning, Changyu Sun, Weina Dai, Ian Groves, Kyoji Ohyama, Sarah Burbridge, Marysia Placzek, Seth Blackshaw

This study uses single-cell RNA-Seq to analyze early chick hypothalamic development, revealing that hypothalamic cells originate from prethalamic-like progenitors and identifying novel molecular regulators.

Cell Reports · Jan 1, 2022Peer-reviewedDevelopmental Biology

Crumbs 2 mediates ventricular layer remodelling to form the adult spinal cord central canal

Christine Mary Tait, Kavitha Chinnaiya, Elizabeth Manning, Mariyam Murtaza, John‐Paul Ashton, Nicholas Furley, Chris J. Hill, C. Henrique Alves, Jan Wijnholds, Kai S. Erdmann, Andrew J. Furley, Penny Rashbass, Raman M Das, Kate G. Storey, Marysia Placzek

The paper shows that Crumbs2 (CRB2) mediates dorsal collapse in the spinal cord by promoting cell delamination and ventricular layer remodelling.

PLoS Biology · Mar 9, 2020Peer-reviewedDevelopmental Biology