BiochemistrybioRxivPreprint
A biased allosteric modulator functions as a molecular glue to induce β2AR dimerization
Jiemin Shen, Teja Peddada, Konstantin E. Komolov…·Brian K. Kobilka
The paper shows that AP-7-168 induces β2AR dimerization by acting as a molecular glue, revealing a new allosteric mechanism for GPCR modulation.
1 citation