Author

Aniruddha Sahasrabuddhe

Amgen (United States)ORCID 0000-0002-3980-0035Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexis CourbetiD· 1 shared Andreas PlückthuniD· 1 shared Andrew S. NorrisiD· 1 shared Danny D. SahtoeiD· 1 shared David A. BakeriD· 1 shared David VeesleriD· 1 shared Florian BüschiD· 1 shared George UedaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperSynthetic Biology

Alexis CourbetORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Novel mechanistic insights for catalytic bioluminescence of mammalian Gaussia Luciferase through mutant and ancestral analysis

Raina M. Borum, Michael B. Lanzillotti, Aniruddha Sahasrabuddhe, John O. Hui, Victoria Cochran Xie, John Ferbas

This study investigates the catalytic mechanism of Gaussia Luciferase through mutant and ancestral analysis, revealing methionine oxidation's role in luminescence and evolutionary changes in substrate turnover.

bioRxiv · Jun 16, 2025 · PreprintBiochemistry

Generation of ordered protein assemblies using rigid three-body fusion

Ivan Vulovic, Qing Yao, Young‐Jun Park, Alexis Courbet, Andrew S. Norris, Florian Büsch, Aniruddha Sahasrabuddhe, Hannes Merten, Danny D. Sahtoe, George Ueda, Jorge A. Fallas, Sara J. Weaver, Yang Hsia, Robert A. Langan, Andreas Plückthun, , David A. Baker

The paper introduces a computational method for designing rigid protein assemblies through three-body fusion and validates it experimentally with mass spectrometry and cryo-EM.

Proceedings of the National Academy of Sciences · May 31, 2021Peer-reviewedSynthetic Biology