Maria Magdalena Klimecka

Evaluation of degron motifs in Escherichia coli using a fluorescent reporter

The paper evaluates degron motifs in Escherichia coli using fluorescent reporter constructs to assess degradation kinetics through endpoint and kinetic measurements.

Human FASTK preferentially binds single-stranded and G-rich RNA

This study identifies the RNA-binding preferences of human FASTK, showing it binds single-stranded G-rich RNA and G-quadruplexes, and protects mitochondrial mRNAs from degradation.

Targeted Protein Degradation in Escherichia coli - depletion of the essential GroEL using CLIPPERs

This paper introduces a method for targeted protein degradation in bacteria using degrader peptides that exploit the ClpXP protease, demonstrating its effectiveness on the essential GroEL protein.