Molecular BiologybioRxivPreprint
Targeted Protein Degradation in Escherichia coli - depletion of the essential GroEL using CLIPPERs
Matylda Anna Izert, Maria Magdalena Klimecka, Anna Antosiewicz…·Maria W. Górna
This paper introduces a method for targeted protein degradation in bacteria using degrader peptides that exploit the ClpXP protease, demonstrating its effectiveness on the essential GroEL protein.
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