Matylda Anna Izert

The paper identifies a new mechanism of kinase inhibition through electrophilic modifications, revealing aspartate conjugation of ULK1 by a chloroacetamide warhead.

The paper evaluates degron motifs in Escherichia coli using fluorescent reporter constructs to assess degradation kinetics through endpoint and kinetic measurements.

This paper introduces a method for targeted protein degradation in bacteria using degrader peptides that exploit the ClpXP protease, demonstrating its effectiveness on the essential GroEL protein.