Matthias Fischer

Single-cell-resolved natural giant virus infections reveal conserved protist immunity

The paper identifies active giant-virus infections in protists and shows conserved antiviral defenses and potential viral counter-defense mechanisms.

Viral infection and virophage co-infection induce distinct remodeling of host lipidome

This study investigates how giant virus and virophage co-infection alter the host lipidome, finding distinct lipid remodeling patterns associated with each infection type.

Strain-level diversity of giant viruses infecting chlorarachniophyte algae in the subtropical North Pacific

The paper describes four isolates of a giant virus infecting chlorarachniophyte algae, highlighting strain-level genetic and epigenetic variation.

Natural history of eukaryotic DNA viruses with double jelly-roll major capsid proteins

The paper uses protein structure modeling to analyze the evolutionary relationships and functional domains of eukaryotic DNA viruses with double jelly-roll capsids, revealing their origin and evolution.

proovframe: frameshift-correction for long-read (meta)genomics

proovframe corrects frameshift errors in long-read (meta)genomics data using protein-to-nucleotide alignments, improving data quality without requiring high sequencing depth.

MOSGA 2: Comparative genomics and validation tools

MOSGA 2 provides advanced genomic analysis tools for annotation, validation, and comparative genomics across multiple datasets.

Four high-quality draft genome assemblies of the marine heterotrophic nanoflagellate Cafeteria roenbergensis

The paper presents four high-quality draft genome assemblies of Cafeteria roenbergensis, enabling evolutionary analysis of heterotrophic protists.