Author

Konstantin M. P. Wolf

Massachusetts General HospitalORCID 0000-0002-4020-0483Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexander Daniel CarliniD· 2 shared Benedikt R. Dürr· 2 shared Junbing ZhangiD· 2 shared Lei ShiiD· 2 shared Liron Bar‐PelediD· 2 shared Marianne Richter· 2 shared Mariko TakahashiiD· 2 shared Nabeel M. BardeesyiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Alexander Daniel CarlinORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 11, 2026

Label-Free Quantification of Microtissue Growth Dynamics Using Optical Flow and Mitosis Detection

Kai Lennard Fastabend, Tassilo von Trotha, Konstantin M. P. Wolf…·Philip Kollmannsberger

This paper quantifies microtissue growth dynamics using optical flow and mitosis detection from label-free brightfield imaging, revealing distinct spatial patterns of cell proliferation and tissue expansion.

DOI 10.64898/2026.08.10.743847

humanimaging

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Molecular BiologybioRxivPreprintMar 11, 2023

Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway

Junbing Zhang, Claire M. Simpson, Jacqueline Berner…·Liron Bar‐Peled

The paper identifies a nucleus-to-mitochondria ROS sensing pathway involving CHK1 and SSBP1 that mediates resistance to platinum-based chemotherapies in ovarian cancers.

DOI 10.1101/2023.03.11.532189

humanproteomics

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Molecular BiologyCell MetabolismPeer-reviewedFeb 24, 2023

NRF2 activation induces NADH-reductive stress providing a metabolic vulnerability in lung cancer

Tommy Weiss‐Sadan, Maolin Ge, Makiko Hayashi…·Liron Bar‐Peled

The paper shows NRF2 activation in KEAP1 wildtype lung cancers causes NADH-reductive stress, making them vulnerable to Complex I inhibition.

158 citationstop 1%

humanbulk RNA-seq

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