Author

Charlotte K. Brierley

Royal Devon & Exeter NHS Foundation TrustORCID 0000-0002-4028-3733Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Abdullah Obaid KhaniD· 1 shared Adam J. MeadiD· 1 shared Aileen Nacorda· 1 shared Alexandros RampotasiD· 1 shared Andrew SingletoniD· 1 shared Anette E. SchragiD· 1 shared Anjum Misbahuddin· 1 shared Anna M. Bulek· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Abdullah Obaid KhanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CAR T cell therapy selectively depletes disease-driving mutant calreticulin cells in xenotransplants and human organoid models of myelofibrosis

Alexandros Rampotas, Zoë C. Wong, Isaac Gannon, Charlotte K. Brierley, Yuqi Shen, Camélia Benlabiod, Ashlyn Chee, Saif Khan, Nawshad Hayder, Gordon Weng-Kit Cheung, Marina Mitsikakou, Eleanor Murphy, Mathieu Ferrari, Anna M. Bulek, Antonio Rodriguez-Romera, , Martin A. Pulè

A first-in-class CAR T-cell therapy targeting mutant calreticulin selectively depletes malignant stem cells in vivo and in fibrotic human organoids.

Science Translational Medicine · Jul 1, 2026Peer-reviewedCancer Biology

Parkinson's Families Project: a UK-wide study of early onset and familial Parkinson's disease

Clodagh Towns, Zih‐Hua Fang, Manuela M. X. Tan, Simona Jasaityte, Theresa M. Schmaderer, Eleanor J. Stafford, Miriam I. Pollard, Russel Tilney, Megan Hodgson, Lesley Wu, Robyn W. Labrum, Jason Hehir, James M. Polke, Lara Mariah Lange, Anthony H.V. Schapira, , Henry Houlden

The paper reports genetic findings from a UK-wide study of early-onset and familial Parkinson's disease, identifying pathogenic variants in known PD genes and highlighting the need for further monogenic causes.

npj Parkinson s Disease · Oct 17, 2024Peer-reviewedGenetic & Genomic Medicine