Author

Anna M. Bulek

Autolus (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Isaac GannoniD· 2 shared Martin A. PulèiD· 2 shared Mathieu FerrariiD· 2 shared Abdullah Obaid KhaniD· 1 shared Abigail Dolor· 1 shared Adam J. MeadiD· 1 shared Alastair HotblackiD· 1 shared Alexander KinnaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Isaac GannonORCID

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Author profile →

2 papers

Recent·Most cited

CAR T cell therapy selectively depletes disease-driving mutant calreticulin cells in xenotransplants and human organoid models of myelofibrosis

Alexandros Rampotas, Zoë C. Wong, Isaac Gannon, Charlotte K. Brierley, Yuqi Shen, Camélia Benlabiod, Ashlyn Chee, Saif Khan, Nawshad Hayder, Gordon Weng-Kit Cheung, Marina Mitsikakou, Eleanor Murphy, Mathieu Ferrari, Anna M. Bulek, Antonio Rodriguez-Romera, , Martin A. Pulè

A first-in-class CAR T-cell therapy targeting mutant calreticulin selectively depletes malignant stem cells in vivo and in fibrotic human organoids.

Science Translational Medicine · Jul 1, 2026Peer-reviewedCancer Biology

Designer small molecule control system based on Minocycline induced disruption of protein-protein interaction.

Ram Jha, Alexander Kinna, Alastair Hotblack, Reyisa Bughda, Anna M. Bulek, Isaac Gannon, F. Tudor Ilca, Christopher G. Allen, Katarina Lamb, Abigail Dolor, Ian Scott, Farhaan Parekh, James Sillibourne, Shaun P Cordoba, Shimobi C. Onuoha, , Martin A. Pulè

The paper develops a small-molecule control system using minocycline to disrupt protein-protein interactions for reversible and dose-dependent control of therapeutic applications.

ACS Chemical Biology · Jan 20, 2024Peer-reviewedMolecular Biology