Cancer BiologybioRxivPreprint
GDF15 reprograms the microenvironment to drive the development of uveal melanoma liver metastases
Sathya Neelature Sriramareddy, Navya Siddarajappa, Jun Sung Park…·Keiran S.M. Smalley
This study identifies GDF15 as a driver of uveal melanoma liver metastasis by reprogramming hepatic stellate cells to promote angiogenesis and matrix deposition.