Mark D. Walsh

This paper demonstrates physical learning in engineered bacteria using a genetically encoded local learning rule that updates analogue weights through environmental inputs and differential growth.

The paper identifies highly conserved cis-regulatory modules in zebrafish and human endoderm that control vertebrate organogenesis and are enriched for neuro-pancreatic transcription factor binding sites.

This paper compares the functional roles of Eomesodermin in zebrafish and mouse, finding functional conservation despite phenotypic differences and revealing its role in left/right organiser formation.

This paper describes a system of engineered bacteria that evolve to play tic-tac-toe, demonstrating complex decision-making through gene circuits.

The paper measures transcriptional bursting using Bayesian methods and shows that polymerase shuttling affects burst size and frequency, with implications for transcriptional noise.