Author

Yina Zhu

University of California San DiegoORCID 0000-0003-0884-3806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cornelis MurreiD· 2 shared Matthew Denholtz· 2 shared Frank AlberiD· 1 shared Hanbin Lu· 1 shared Ke Qin GongiD· 1 shared Mark P. Kamps· 1 shared Simon Döhrmann· 1 shared Takeshi IsodaiD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Cornelis MurreORCID

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2 papers

Recent·Most cited

GenomicsGenes & DevelopmentPeer-reviewedFeb 1, 2020

Upon microbial challenge human neutrophils undergo rapid changes in nuclear architecture to orchestrate an immediate inflammatory gene program

Matthew Denholtz, Yina Zhu, Zhaoren He…·Cornelis Murre

This study shows that human neutrophils reposition inflammatory genes to a transcriptionally permissive compartment within hours of microbial exposure, enabling rapid transcriptional responses.

39 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivJan 15, 2017

Comprehensive characterization of neutrophil genome topology

Yina Zhu, Ke Qin Gong, Matthew Denholtz…·Cornelis Murre

This study characterizes the genome topology of neutrophils, revealing super-contraction and chromatin reorganization during differentiation.

77 citations

humanDNA methylation

𝕏 PostBluesky