Author

Tanja Petnicki‐Ocwieja

Tufts UniversityORCID 0000-0002-4048-5300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Archana DhasarathyiD· 1 shared Catherine Ayn BrissetteiD· 1 shared Christopher C. WellsiD· 1 shared Eleanor Astley· 1 shared Jeffrey S. BourgeoisiD· 1 shared Kaitlyn GuraiD· 1 shared Linden T. HuiD· 1 shared Michael Hill· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Archana DhasarathyORCID

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2 papers

Recent·Most cited

Spatial Transcriptomic Profiling Reveals Microenvironment-Dependent Immune Signatures in a Lyme Arthritis model

Kaitlyn Gura, Mollie Hostetter, Veena Potluri, Michael Hill, Sarah Johnson, Yuelin Zhong, Eleanor Astley, Tanja Petnicki‐Ocwieja, Suba Nookala, Catherine Ayn Brissette, Archana Dhasarathy

This study uses spatial transcriptomics to analyze immune signatures in Lyme arthritis, showing spatially restricted gene expression patterns and microenvironment-dependent immune responses in infected mouse joints.

bioRxiv · Jun 25, 2026 · PreprintMicrobiology

Differentiating Peromyscus leucopus bone marrow-derived macrophages for characterization of responses to Borrelia burgdorferi and lipopolysaccharide

Christopher C. Wells, Tanja Petnicki‐Ocwieja, Shumin Tan, Stephen C. Bunnell, Sam R. Telford, Linden T. Hu, Jeffrey S. Bourgeois

This study differentiates Peromyscus leucopus bone marrow-derived macrophages and compares their responses to Borrelia burgdorferi and lipopolysaccharide with C57BL/6J macrophages, finding modest transcriptomic differences.

Infection and Immunity · May 27, 2025Peer-reviewedImmunology