Sam R. Telford

This study genetically engineers mice to produce a protective antibody against Lyme disease, demonstrating heritable immunity that interrupts pathogen transmission.

The paper investigates how different genotypes of Deer tick virus (DTV) are perpetuated through various transmission modes, finding that some genotypes are linked to specific host associations while others are not.

This study differentiates Peromyscus leucopus bone marrow-derived macrophages and compares their responses to Borrelia burgdorferi and lipopolysaccharide with C57BL/6J macrophages, finding modest transcriptomic differences.

The paper compares transcriptomic responses to larval Ixodes scapularis bites in Peromyscus leucopus, Mus musculus, and humans, finding distinct immune activation patterns.

The paper identifies a focal site of Heartland virus in Georgia, generates new genome sequences, and finds regional clustering and recent spread of the virus.

This study identifies common deletions and defective RNAs in field-collected Powassan virus-infected ticks and shows changes in deletion expression after cell passage.