Spatial Transcriptomic Profiling Reveals Microenvironment-Dependent Immune Signatures in a Lyme Arthritis model
Kaitlyn Gura, Mollie Hostetter, Veena Potluri, Michael Hill, Sarah Johnson, Yuelin Zhong, Eleanor Astley, Tanja Petnicki‐Ocwieja, Suba Nookala, Catherine Ayn Brissette, Archana Dhasarathy
This study uses spatial transcriptomics to analyze immune signatures in Lyme arthritis, showing spatially restricted gene expression patterns and microenvironment-dependent immune responses in infected mouse joints.
bioRxiv · Jun 25, 2026 · PreprintMicrobiology