Jean‐René Huynh

This study identifies His2Av as a critical histone variant that regulates piRNA pathway activation and prevents genome instability during oogenesis in Drosophila.

The paper identifies meiotic genes expressed during mitosis in Drosophila females and shows that some are translated but not functionally active in mitotic cells.

This study shows that Spo11 knockout in Clytia hemisphaerica disrupts meiotic synapsis and chromosome segregation, revealing conserved meiotic mechanisms across eukaryotes.

The paper investigates homologous chromosome pairing in Drosophila males, showing that despite lacking synaptonemal complexes and recombination, pairing occurs via SC proteins, the SUN/KASH complex, and microtubules, with slower dynamics compensated by longer cell cycles.

The paper develops a bioinformatic pipeline to analyze tRNA fragments (tRFs) in Drosophila mutants, revealing how defects in tRNA biogenesis affect tRF and snoRNA populations.

The paper shows that contractile cortical waves and adhesion are essential for germline cells to sort into primordial follicles with somatic cells in Drosophila.