Author

Nicolas Macaisne

Centre National de la Recherche ScientifiqueORCID 0000-0002-0109-9845Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ana María Vallés· 2 shared Jean‐René HuynhiD· 2 shared Laurine Dal Toe· 2 shared Thomas RubiniD· 2 shared Anahi Molla‐HermaniD· 1 shared Christophe AntoniewskiiD· 1 shared Clara Guilleman· 1 shared Isabelle GauguéiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Ana María Vallés

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3 papers

Recent·Most cited

Transcriptomic analysis of meiotic genes during the mitosis-to-meiosis transition in Drosophila females

Ana María Vallés, Thomas Rubin, Nicolas Macaisne, Laurine Dal Toe, Anahi Molla‐Herman, Christophe Antoniewski, Jean‐René Huynh

The paper identifies meiotic genes expressed during mitosis in Drosophila females and shows that some are translated but not functionally active in mitotic cells.

Genetics · Sep 3, 2024Peer-reviewedDevelopmental Biology

Pre-meiotic pairing of homologous chromosomes during Drosophila male meiosis

Thomas Rubin, Nicolas Macaisne, Ana María Vallés, Clara Guilleman, Isabelle Gaugué, Laurine Dal Toe, Jean‐René Huynh

The paper investigates homologous chromosome pairing in Drosophila males, showing that despite lacking synaptonemal complexes and recombination, pairing occurs via SC proteins, the SUN/KASH complex, and microtubules, with slower dynamics compensated by longer cell cycles.

Proceedings of the National Academy of Sciences · Nov 14, 2022Peer-reviewedDevelopmental Biology

Meiotic Double-Strand Break Proteins Influence Repair Pathway Utilization

Judith L. Yanowitz, Nicolas Macaisne, Zebulin Kessler

The paper shows that meiotic DSB proteins influence repair pathway choice, specifically affecting TMEJ and SSA when HR is compromised in C. elegans.

Genetics · Sep 21, 2018Peer-reviewedGenetics