Hongbo Zhang

A human embryonic limb cell atlas resolved in space and time

This paper creates a human embryonic limb cell atlas using single-cell and spatial transcriptomics, identifying novel cell populations and developmental patterns.

A method for differential expression analysis and pseudo- temporal locating and ordering of genes in single-cell transcriptomic data

DEAPLOG improves differential expression analysis and pseudo-temporal gene ordering in single-cell transcriptomic data, showing higher accuracy and efficiency than existing methods.

Human skeletal muscle ageing atlas

This study creates a single-cell and single-nucleus transcriptomic atlas of human skeletal muscle ageing, revealing mechanisms in muscle stem cells, myofibers, and the microenvironment.

Cells and gene expression programs in the adult human heart

The paper characterizes the cellular composition and gene expression of the adult human heart using single-cell transcriptomics, identifying distinct cell types and their functional roles.