GenomicsBriefings in BioinformaticsPeer-reviewed
Detecting Full-Length EccDNA with FLED and long-reads sequencing
Fu‐Yu Li, Wenlong Ming, Wenxiang Lu…·Yunfei Bai
The paper introduces FLED, a method combining rolling circle amplification and nanopore sequencing to detect full-length eccDNAs, identifying over 5,000 per sample in human cell lines.
14 citations