NeurosciencebioRxivPreprint
A combinatorial approach to ALS therapies in the PrP.TDP43-315 model of ALS; complications and tribulations
Susan Fromholt, Amanda Lopez, Guilian Xu…·David Borchelt
The paper tests drug combinations in a TDP43-ALS mouse model to extend lifespan but finds no substantial lifespan extension despite dietary interventions.
DOI 10.1101/2024.10.01.616092