Single-Soma Deep RNA sequencing of Human DRG Neurons Reveals Novel Molecular and Cellular Mechanisms Underlying Somatosensation
Huasheng Yu, Saad S. Nagi, Dmitry Usoskin, Yizhou Hu, Jussi Kupari, Otmane Bouchatta, Hanying Yan, Suna Li Cranfill, Mayank Gautam, Yijing Su, You Lu, James P. Wymer, Max E. Glanz, Phillip J. Albrecht, Hongjun Song, , Wenqin Luo
This study develops a method to sequence individual human DRG neuron somas, identifies 16 neuronal types, and reveals human-specific nociceptor types and potential drug targets.
Nature Neuroscience · Nov 4, 2024Peer-reviewedNeuroscience