Author

Susan Fromholt

University of Florida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

David BorcheltiD· 2 shared Amanda Lopez· 1 shared Carmelina Gorski· 1 shared Guilian M. XuiD· 1 shared Guilian Xu· 1 shared James P. WymeriD· 1 shared Karen N. McFarlandiD· 1 shared Paramita ChakrabartyiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

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10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

David BorcheltORCID

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2 papers

Recent·Most cited

A combinatorial approach to ALS therapies in the PrP.TDP43-315 model of ALS; complications and tribulations

Susan Fromholt, Amanda Lopez, Guilian Xu, Qing Lü, James P. Wymer, David Borchelt

The paper tests drug combinations in a TDP43-ALS mouse model to extend lifespan but finds no substantial lifespan extension despite dietary interventions.

bioRxiv · Oct 1, 2024 · PreprintNeuroscience

Human APOE allelic variants suppress the formation of diffuse and fibrillar Aβ deposits relative to mouse Apoe in transgenic mouse models of Alzheimer amyloidosis

Guilian M. Xu, Patricia Sacilotto, Carmelina Gorski, Parul Bali, Susan Fromholt, Quan Vo, Karen N. McFarland, Qing Lu, David Borchelt, Paramita Chakrabarty

This study shows human APOE variants reduce both diffuse and fibrillar Aβ deposits in transgenic mouse models compared to mouse Apoe, with APOE3 more effective than APOE4 in some contexts.

bioRxiv · Apr 30, 2024 · PreprintNeuroscience