Author

Shen‐Ju Chou

Institute of Cellular and Organismic Biology, Academia SinicaORCID 0000-0002-4103-7286Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Che-Yi LiniD· 1 shared Chen-Hsin Albert YuiD· 1 shared Chia-Fang Wang· 1 shared Heiko J. LuhmanniD· 1 shared Jenq‐Wei YangiD· 1 shared Jr‐Kai YuiD· 1 shared Kun‐Hai Yeh· 1 shared Linbi CaiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperEvolutionary Biology

Che-Yi LinORCID

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3 papers

Recent·Most cited

A Distinct Layer 1 Astrocyte Program Shapes Perisynaptic Structure and Calcium Signaling in Mouse Motor Cortex

Srimayee Bhattacharjee, Kun‐Hai Yeh, Ping-Yen Wu, Ming-Xi Pan, Tzu-Hsien Liu, Zhao-Bo Tsai, Sok‐Keng Tong, Zi-Hui Zhuang, Yu-Min Huang, Shen‐Ju Chou, Shu‐Ling Chiu, Ming‐Yi Chou, Chen-Hsin Albert Yu, Yu‐Wei Wu

The paper identifies a distinct Layer 1 astrocyte program in mouse motor cortex linked to specialized structure and calcium signaling, showing that Id1/Id3 deletion disrupts this program.

bioRxiv · Mar 17, 2026 · PreprintNeuroscience

A 3D Amphioxus Brain Atlas Illuminates the Blueprint of the Ancestral Chordate Brain

Che-Yi Lin, Wen-Hsin Hsu, Mei‐Yeh Jade Lu, Yi-Hua Chen, Yi‐Chih Chen, Yi‐Hsien Su, Shen‐Ju Chou, Jr‐Kai Yu

This study creates a 3D amphioxus brain atlas using single-nucleus RNA-seq and spatial transcriptomics, revealing ancestral brain organization and highlighting vertebrate innovations.

bioRxiv · Nov 27, 2025 · PreprintEvolutionary Biology

Identification of a developmental switch in information transfer between whisker S1 and S2 cortex in mice

Linbi Cai, Jenq‐Wei Yang, Shen‐Ju Chou, Chia-Fang Wang, Heiko J. Luhmann, Theofanis Karayannis

The paper identifies a developmental switch in information transfer from wS1 to wS2 cortex in mice, showing excitatory connections emerge after the first post-natal week.

Journal of Neuroscience · May 2, 2022Peer-reviewedNeuroscience