Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock
Andrea Brenna, Micaela Borsa, Gabriella Sarò, Jürgen A. Ripperger, Dominique A. Glauser, Zhihong Yang, Antoine Adamantidis, Urs Albrecht
This study shows that Cdk5 activity, modulated by light, gates rapid circadian phase shifts by regulating calcium influx and signaling pathways in SCN neurons.
bioRxiv · Feb 8, 2024Neuroscience