Min Whan Jung

Selective engagement of prefrontal VIP neurons in reversal learning

This study investigates the role of VIP neurons in mouse medial prefrontal cortex during reversal learning, finding they are critical for rapid behavioral adjustments but not for incremental learning.

Hierarchical gradients of multiple timescales in the mammalian forebrain

The paper shows that intrinsic and task-related neural timescales increase hierarchically across mammalian cortices, but thalamic timescales differ from this pattern.

Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions

The paper identifies cortical neuron ensembles that couple differently to hippocampal SWRs in distinct subregions and proposes their role in cognitive map formation.

Suppressed prefrontal neuronal firing variability and impaired social representation in IRSp53-mutant mice

This study examines neuronal firing patterns in IRSp53-mutant mice during social approach, finding reduced variability and impaired social information encoding in the medial prefrontal cortex.

Parallel processing of working memory and temporal information by distinct types of cortical projection neurons

This study identifies distinct roles of IT and PT neurons in working memory and temporal processing during a delayed response task in mice.

Enhanced negative emotional processing limits behavioral flexibility in a mouse model of autism spectrum disorder

This study shows that enhanced negative emotional processing in Shank2-KO mice impairs reversal learning, suggesting a link between emotional processing and behavioral flexibility in ASD.

Transient effect of mossy fiber stimulation on spatial firing of CA3 neurons

This study shows that optogenetic mossy fiber stimulation transiently alters CA3 spatial firing in mice, but does not permanently change place fields, challenging the idea that mossy fibers impose teaching signals.